Alzheimers Disease
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Links: "Efficacy and Safety of Cholinesterase Inhibitors in Alzheimer's Disease" Lanctot K.L., et al., Canad. Med. Assoc. Journal, Sept 16, 2003; 169 (6), pp 557-564. These are the only drugs marketed for treatment in Alzheimer's and have not been validated for Efficacy and Safety due to only modest therapeutic effect and significant rates of adverse effects. (86 references) to AMERICAN ACADEMY OF ANTI-AGING MEDICINE at: http://www.worldhealth.net/index.php?p=230 Factors linked to causes of Alzheimers:
Factors thought to be helpful in prevention and treatment:
In response to a recent request we had for Zinc
electrodes, there is above a recent article related to the effect
of Zinc on Alzheimer's which will be of interest. On the
other hand Zinc is essential to proper Thymus Gland and Immune
System function. Thymus gland hormone (Thymulin) contains Zinc. Zinc
absorption is greatly reduced in aging humans and should be
supplemented in the diet and has been shown to induce regrowth of an
atrophied Thymus.; cf "The Zinc-Melatonin Relationship;
Effect of Zinc on the Thymus" Mocchegiani e., Pierpaoli W.et al,
Annal of New York Acad. of Sciences, 1994. The article goes on to say
on page 300 that unbound Zinc (presumably colloidal metallic
particles) is inactive and inhibits the active (salt) form of Zinc of
which we need about 30 mg per day as for example Zinc Citrate.
"Zinc Linked to Alzheimer's Plaques" Results of a recent study have revealed that the formation of the amyloid plaques associated with Alzheimer's disease may depend on zinc released by nerve cells. Researchers from South Korea who bred mice that were prone to developing Alzheimer-like brain plaques but which lacked a zinc-transporting gene called ZnT3 discovered that mice lacking ZnT3 developed significantly fewer and smaller plaques than Alzheimer's-prone mice with the gene. Thus suggesting that zinc plays a significant role in plaque formation. If proven, the results suggest that it may be possible to treat the neurodegenerative disease by developing drugs that preventing zinc from reacting with amyloid protein. SOURCE/REFERENCE: Proceedings of the National Academy of Sciences Early Edition 2002; 99 at http://www.worldhealth.net/index.php?p=230,215 It is evident from the research literature that since Microbial and Free Radical effects are important in the cause of Alzheimers, then antimicrobial, antioxidant and anti-inflammatory substances should be considered and studied.
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